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目的:了解慢性乙型病毒性肝炎(CHB)患者的特点,为CHB防治提供更多的参考。方法:收治慢性乙型病毒性肝炎患者7 880例,回顾性分析其临床资料。结果:抗HBV治疗中单用替比夫定患者最多,其次为单用干扰素及单用恩替卡韦。一半以上的患者治疗后HBV-DNA可低于正常值下限。结论:临床工作中,应根据慢性乙型病毒性肝炎患者的特点选择合适的防治方案。
Objective: To understand the characteristics of patients with chronic hepatitis B (CHB) and provide more references for the prevention and treatment of CHB. Methods: A total of 7 880 patients with chronic hepatitis B were admitted. The clinical data were retrospectively analyzed. Results: The patients receiving telbivudine alone had the most anti-HBV treatment, followed by interferon alone and entecavir alone. More than half of patients after treatment HBV-DNA may be lower than the lower limit of normal. Conclusion: In clinical work, we should choose the appropriate prevention and treatment plan according to the characteristics of patients with chronic hepatitis B virus.