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68例晚期妊娠孕妇除外胎位异常头盆不称和卡孕栓应用禁忌症后,用卡孕栓阴道后穹窿给药终止妊娠。按孕周初定首次给药量根据宫缩强度和产程进展,决定4~6h后给药与否和给药量。最多给药次数5次,最大给药总量2.33mg。以给药48h内出现规律宫缩为引产有效标准,引产有效率为97.05%。引产过程中无先兆子宫破裂和子宫破裂发生,无孕产妇死亡和胎婴儿意外死亡,胎儿宫内窒息发生率11.48%,新生儿轻重度窒息发生率分别为6.6%和1.6%。研究结果表明:卡孕栓用于晚期妊娠引产是有效的和安全的。加强胎心宫缩监护等措施,及早发现和处理胎儿窘迫,可进一步提高引产的安全性。
68 cases of late pregnancy except pregnant women with abnormal fetal head basin anomalies and carboplatin in contraindications to the application of cardiotomy suppository vaginal fornix administration termination of pregnancy. According to the initial gestational age given dose according to the contractions and labor progress, decided to 4 ~ 6h after administration or not and dose. The maximum number of doses 5 times, the maximum dose of 2.33mg. 48h to give regular contractions within the effective standard for induction of labor, induction of labor was 97.05%. Induction of uterine rupture without rupture and uterine rupture occurred, no maternal deaths and fetal infant deaths, the incidence of intrauterine asphyxia was 11.48%, the incidence of neonatal asphyxia were 6.6% and 1.6 %. The results show that: carbowime suppositories for late pregnancy induction of labor is effective and safe. Strengthening fetal heart rate monitoring and other measures of contractions, early detection and treatment of fetal distress, can further improve the safety of induced labor.