目的:研究电磁脉冲(electromagnetic pulse,EMP)对心肌闰盘缝隙连接蛋白43(Cx43)的作用特点。方法:以SD大鼠为研究对象,用EMP照射大鼠,照后各时点取其左心室、右心室、室间隔和心房,用硝酸镧示踪法,电子显微镜观察闰盘形态学变化,用real-time PCR和Western blot方法检测Cx43在转录水平和蛋白水平表达量的变化。结果:EMP组闰盘间隙镧颗粒沉 Objective: To study the effect of electromagnetic pulse (EMP) on the myocardial intercalated gap junction protein 43 (Cx43). Methods: Sprague-Dawley rats were used as experimental subjects. EMPs were used to irradiate rats. The left ventricle, right ventricle, septum and atrium were taken at different time points. The morphology of intercalated disc was observed by electron microscope. Real-time PCR and Western blot were used to detect the expression of Cx43 at the transcription and protein levels. Results: EMP group intercalated disc gap lanthanum particles Shen