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目的探讨消化道恶性肿瘤患者血清CEA与CT检查结果并进行对比。方法共纳入85例疑似为消化道恶性肿瘤的患者,入院后均采用CT及血清CEA检测,并行病理检查作为金标准对上述检查方法进行评价。结果 85例患者确诊为消化道恶性肿瘤60例,非消化道恶性肿瘤25例,以此为金标准;血清CEA灵敏度为81.7%,特异度为60.0%,阳性似然比为0.83,阴性似然比0.58;CT灵敏度为90.0%,特异度为92.0%,阳性似然比为0.96,阴性似然比0.79。联合诊断价值显示并联灵敏度为98.2%,特异度为55.2%;串联灵敏度为73.5%,特异度为96.8%。结论单独CT对消化道恶性肿瘤的诊断价值高于血清CEA,但两者联合检验有更好的诊断价值,因此两者联合检验可作为消化道恶性肿瘤诊断的重要方法 。
Objective To investigate the results of serum CEA and CT in patients with gastrointestinal cancer and compare the results. Methods A total of 85 patients with suspected malignant gastrointestinal cancer were enrolled in the study. CT and serum CEA were used after admission. The pathological examination was used as the gold standard to evaluate the above methods. Results 85 patients were diagnosed as gastrointestinal malignant tumors in 60 cases, 25 cases of non-gastrointestinal malignancies, as the gold standard; serum CEA sensitivity was 81.7%, specificity was 60.0%, positive likelihood ratio was 0.83, negative likelihood Than 0.58; CT sensitivity was 90.0%, specificity was 92.0%, positive likelihood ratio was 0.96, negative likelihood ratio 0.79. The combined diagnostic value showed that the parallel sensitivity was 98.2% and the specificity was 55.2%, the sensitivity of series was 73.5% and the specificity was 96.8%. Conclusion The diagnostic value of CT alone is higher than that of serum CEA in the diagnosis of gastrointestinal malignancies. However, the combination of these two methods has better diagnostic value. Therefore, the combined test can be used as an important method for the diagnosis of gastrointestinal malignancies.