论文部分内容阅读
女性癫痫结婚率较低，与其同胞姐妹比较，结婚率分别为60．4％和83．7％，＜10岁发病者结婚率仅44．8％。女性癫痫妊娠率低于对照组，而生一胎的多于对照组（37．9％和24％）。癫痫本身和各种抗癫痫药均可导致女性癫痫病人的生殖内分泌改变，主要表现有月经不调、绝经期提前、性功能低下、卵巢多囊性改变、性激素结合球蛋白升高、雌二醇下降、促黄体生成素轻度减少，而睾酮、促卵泡素和催乳素无改变。雌激素可诱发癫痫，孕激素有抗癫痫作用，近来有用一种雌激素拮抗剂─氯■酚胺治疗黄体功能不全所致的部分发作型癫痫，取得较好疗效。
The marriage rate of female epilepsy was lower, compared with that of sibling sisters, the marriage rates were 60.4% and 83.7% respectively. The incidence of marriage was only 44.8% in those <10 years of age. Pregnancy rates in women with epilepsy were lower than those in the control group, with more births than controls (37.9% and 24%). Epilepsy itself and a variety of anti-epileptic drugs can lead to reproductive and endocrine changes in women with epilepsy, the main manifestations of irregular menstruation, early menopause, sexual dysfunction, polycystic ovarian changes, elevated sex hormone binding globulin, estradiol Decreased, luteinizing hormone slightly reduced, while testosterone, follicle stimulating hormone and no change. Estrogen can induce epilepsy, progesterone has antiepileptic effect, the recent use of an estrogen antagonist ─ chlorine ■ phenolic amine treatment of corpus luteum partial seizures caused by partial epilepsy, and achieved good results.