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老年人日益增加,且常患多种疾病,故在整个人口中用药较多且用药种类亦显著增多,如美国每年65岁以上患者处方比65岁以下处方多3倍。占人口总数12%的老人用药量为全国用药量的20～25%。英国30%的药物用于65岁以上的患者,75岁以上的老人3/4是常规用药者,其中2/3的人每天1--3种,1/3的人每天4--6种药。老年人许多重要脏器的储备能力和对内环境的调节功能下降,因此药物不良反应的发生率随年龄增加而增
The increasing number of the elderly and often suffering from a variety of diseases makes it more common in the entire population and significantly increases the types of medication. For example, in the United States, prescriptions for patients over the age of 65 each year are three times more likely to be prescribed than those under the age of 65. The dosage of the elderly, accounting for 12% of the total population, ranges from 20% to 25% of the national dosage. Thirty percent of medications in the UK are for patients over 65 years of age and 3/4 of 75 years of age are routinely prescribed, with two thirds of them daily and one to three daily, and one third daily ranging from four to six medicine. Many elderly elderly reserve capacity and regulatory function of the internal environment decreased, so the incidence of adverse drug reactions with age increased