证明链霉素在小鼠和人类抗麻风菌感染的作用已经有过许多报道。作者以前报道了卡那霉素、链霉素和氨基羟丁基卡那霉素极显著的杀灭麻风菌的作用及庆大霉素和托普霉素缺乏明显的杀菌作用。还报道过 DDS的最小有效鼠食谱浓度不加强链霉素对麻风菌的杀菌作用。在这些研究中,氨基甙类是每天在腹膜腔内以高剂量给药的。口服氨基甙类不吸收,在许多麻风病区,每天注射在 There have been many reports of the role of streptomycin in anti-leprosy infections in mice and humans. The authors previously reported kanamycin, streptomycin, and amikacin extremely significant effects of killing leprosy and the absence of significant bactericidal effects of gentamicin and tobramycin. It has also been reported that the minimum effective murine recipe concentration of DDS does not enhance the bactericidal effect of streptomycin on leprosy. In these studies, aminoglycosides are administered daily at high doses in the peritoneal cavity. Oral aminoglycosides are not absorbed in many leprosy areas and are injected daily