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在从近江牡蛎（Ｃｒａｓｓｏｓｔｒｅａ ｒｉｖｕｌａｒｉｓ）软体部分提纯得到纯度均一的铜锌超氧化物歧化酶（Ｃｕ，Ｚｎ－ＳＯＤ）的基础上，对该酶的稳定性进行了研究。结果表明，该酶的水溶液在 ６５℃时活力稳定，而该酶的干品在 １℃／ｍｉｎ程序升温时在５８． ４℃有一尖锐的吸热峰。在 ｐＨ为 ５． ２～１０．０的范围内该酶的活力不受影响。该酶对 Ｈ_２Ｏ_２和 ＫＣＮ均敏感，且能耐受 Ｔｓｕｃｈｉｈａｓｈｉ氏试剂的作用。一些氧化、还原剂、变性剂可改变酶的活力。差示扫描量热分析（Ｄｉｆｆｅｒｅｎｔｉａｌ Ｓｃａｎｎｉｎｇ Ｃａｌｏｒｉｍｅｔｒｙ，ＤＳＣ）发现，该酶在不同的升温速率下以及不同浓度的Ｈ_２Ｏ_２处理对酶的稳定性的影响与猪血、牛血ＳＯＤ均有差异。
The stability of this enzyme was studied on the basis of the purification of Cu, Zn-SOD with uniform purity from the soft part of Crassostrea rivularis. The results showed that the aqueous solution of the enzyme was stable at 65 ° C while the dried product of the enzyme had a temperature of 58 ° C at 1 ° C / min. 4 ℃ have a sharp endothermic peak. At pH 5. The activity of this enzyme is not affected in the range of 2 to 10.0. The enzyme is sensitive to both H 2 O 2 and KCN and is able to tolerate Tsuchihashi’s reagent. Some oxidation, reducing agents, denaturants can change the enzyme activity. Differential Scanning Calorimetry (DSC) showed that the effect of the enzyme at different heating rates and different concentrations of H 2 O 2 treatment on the stability of the enzyme was different from those of porcine blood and bovine blood SOD.