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为了探讨治喘伏贴灵对幼鼠的平喘作用 ,采用药物引喘法和用放射免疫法测量幼鼠血浆中环腺苷酸(cAMP)与环鸟苷酸 (cGMP)的含量。结果 :治喘伏贴灵对乙酰胆碱和组织胺混合引喘的幼年豚鼠能明显延长哮喘发生的潜伏期 ,减少发生百分率 ;并能提高幼鼠血浆cAMP/cGMP比值。提示治喘伏贴灵具有明显的平喘作用。
In order to explore the antiasthmatic effects of Zhichuanfufuling on pups, the concentrations of cAMP and cGMP in plasma of pups were measured by drug induced asthma and radioimmunoassay. RESULTS : The guinea pigs with acetylcholine and histamine mixed asthma induced by Zhifu Futieling could significantly prolong the latency of asthma and reduce the percentage of occurrence. The plasma cAMP/cGMP ratio could also be increased in young rats. Tips Zhifu Fu Ti Ling has obvious asthma effect.