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目的:观察自拟降脂汤联合阿托伐他汀治疗高脂血症的临床疗效。方法:将80例高脂血症患者随机分为两组各40例,治疗组予自拟降脂汤联合阿托伐他汀治疗;对照组予阿托伐他汀治疗,两组均治疗3个月为1个疗程,治疗结束后观察两组患者血清总胆固醇、甘油三酯、低密度脂蛋白胆固醇、高密度脂蛋白胆固醇水平的变化。结果:治疗后两组患者总胆固醇、甘油三酯、低密度脂蛋白胆固醇均明显降低(P<0.05),治疗组明显优于对照组。与对照组比较,治疗组高密度脂蛋白胆固醇有上升,但差异无统计学意义(P>0.05);两组总有效率比较,治疗组优于对照组,差异有统计学意义(P<0.05)。结论:自拟降脂汤联合阿托伐他汀治疗高脂血症患者有较好疗效。
Objective: To observe the clinical efficacy of self-made Jiangzhi Decoction combined with atorvastatin in the treatment of hyperlipidemia. Methods: Eighty patients with hyperlipidemia were randomly divided into two groups of 40 patients. The treatment group was given self-made Jiangzhi Decoction combined with atorvastatin. The control group was treated with atorvastatin. Both groups were treated for 3 months For a course of treatment, after treatment, the changes of serum total cholesterol, triglyceride, low density lipoprotein cholesterol and high density lipoprotein cholesterol in two groups were observed. Results: After treatment, the total cholesterol, triglyceride and low density lipoprotein cholesterol in the two groups were significantly decreased (P <0.05), the treatment group was significantly better than the control group. Compared with the control group, the treatment group had an increase in high-density lipoprotein cholesterol, but the difference was not statistically significant (P> 0.05); the total effective rate in the two groups was better than that in the control group, with significant difference (P <0.05 ). Conclusion: Self-made Jiangzhi Decoction combined with atorvastatin treatment of patients with hyperlipidemia have a good effect.