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肾脏是体内合成血栓素A_2(TXA_2)、前列环素(PGI_2)和前列腺素E_2(PGE_2)等激素的主要器官.TXA_2和PGI_2之间存在一种拮抗和平衡关系.放免分析法检测TXB_2和6-Keto-PGF_(1a)(TXA_2和PGI_2代谢产物)及临床应用已有报道.用在肾移植急性排斥上报道甚少.
The kidney is the main organ for the synthesis of TXA_2, PGI_2 and PGE_2, and there is an antagonistic and balance relationship between TXA_2 and PGI_2. -Keto-PGF_ (1a) (TXA_2 and PGI_2 metabolites) and its clinical application have been reported.It has been reported in acute rejection of renal allografts.