论文部分内容阅读
[目的]探讨住院患者非白念珠菌感染和白念珠菌感染的流行病学特点以及发生的相关危险因素。[方法]采用病例对照研究方法,对256例非白念珠菌感染者、834例白念珠菌感染者以及1220例无真菌感染者进行危险因素比较,应用SPSS13.0统计软件进行统计学分析。[结果]年龄、病程、住院时间、白细胞及中性粒细胞计数减少、白蛋白降低、基础疾病、预防性使用抗真菌药物、抗菌素、激素、免疫抑制剂、有创的检查和治疗是白念珠菌和非白念珠菌感染的共同危险因素。患有泌尿系统疾病、使用激素更容易引起非白念珠菌感染,使用免疫抑制剂更容易引起白念珠菌感染。[结论]念珠菌感染的流行病学是复杂而变化的,白念珠菌和非白念珠菌感染的危险因素也是不同的。非白念珠菌感染已经成为一个不容忽视的问题。早期诊治基础疾病、合理规范应用检查和治疗手段、适当缩短住院时间是预防念珠菌感染的关键。
[Objective] To investigate the epidemiological characteristics of non-Candida albicans and Candida albicans inpatients and related risk factors. [Methods] The risk factors of 256 non-Candida albicans infected persons, 834 Candida albicans infected persons and 1220 non-fungal infected persons were compared using the case-control study. SPSS13.0 statistical software was used for statistical analysis. [Results] Age, duration of disease, length of hospital stay, reduction of white blood cell and neutrophil count, reduction of albumin, underlying diseases, prophylactic use of antifungal drugs, antibiotics, hormones, immunosuppressive agents, invasive examination and treatment were white rosary beads Common risk factors for bacterial and non-albicans infections. Suffering from urological diseases, the use of hormones more likely to cause non-Candida albicans infection, the use of immunosuppressive agents more likely to cause C. albicans infection. [Conclusion] The epidemiology of Candida infection is complex and variable, and the risk factors of Candida albicans and non-Candida albicans infection are also different. Non-Candida albicans infection has become a problem that can not be ignored. Early diagnosis and treatment of underlying diseases, reasonable application of standardized examination and treatment, appropriate shortening the hospital stay is the key to preventing Candida infection.