Lopez报道有关钙通道阻滞剂对高血压病人左心室肥大消退作用的资料是不完全的。然而有关维拉帕米的几项临床研究成果可用来阐明这个问题。Schmieder等报道了7例用维拉帕米缓释剂治疗的病人,疗程8～12周,用M型超声心动图进行评估,结果6%病人的左心室质量指数下降,并相对地减少了心壁的厚度。 Lopez reported incomplete calcium channel blockers on regression of left ventricular hypertrophy in hypertensive patients. However, several clinical studies of verapamil can be used to elucidate this issue. Schmieder et al. Reported 7 patients treated with verapamil sustained-release agent for 8 to 12 weeks. M-mode echocardiography was used to evaluate the results. 6% of patients showed a decrease in left ventricular mass index and a relative decrease in heart size Wall thickness.