作者报道3例有意超量服用左旋甲状腺素造成人为甲亢,但发生猝死的病例,推测死于心室纤颤。其中1例患者女性,50岁,为减轻体重而滥用左旋甲状腺素多年,有时服至600～800μg/d,造成人为甲状腺毒症,但临床缺乏典型的甲亢症状和体征。患者以胸疼入院,心电图示:心房纤颤,室率155/min,普遍性非特异 ST-T 改变。当天用地高辛后心律转为窦性。次日作甲状腺功能检查,血清总甲状腺素 The authors report 3 cases of intentional overdose of levothyroxine cause of hyperthyroidism, but the case of sudden death, presumably died of ventricular fibrillation. One patient, female, 50 years old, abused levothyroxine for weight loss for many years, sometimes to 600 ~ 800μg / d, resulting in human thyrotoxicosis, but the clinical lack of typical symptoms and signs of hyperthyroidism. Patients with chest pain admitted, ECG shows: atrial fibrillation, room rate 155 / min, universal non-specific ST-T changes. After the day with digoxin into the sinus rhythm. The next day for thyroid function tests, serum total thyroxine