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目的:探讨风湿性心脏病合并心衰患者采用曲美他嗪结合卡维地洛治疗的效果。方法:将82例风湿性心脏病合并心衰患者分为两组;对照组给予常规治疗;观察组在常规治疗的基础上,采用曲美他嗪结合卡维地洛治疗;对比两组治疗后疗效及左心室射血分数(LVEF)、6分钟步行距离(6MWT)、心力衰竭评分水平。结果:观察组总有效率显著高于对照组(P<0.05);观察组治疗后LVEF、6MWT水平显著高于对照组,心力衰竭评分显著低于对照组(P<0.05);两组均无明显不良反应发生。结论:曲美他嗪结合卡维地洛治疗风湿性心脏病合并心衰,能显著提高疗效,改善心功能。
Objective: To investigate the effect of trimetazidine combined with carvedilol in patients with rheumatic heart disease and heart failure. Methods: 82 cases of rheumatic heart disease with heart failure were divided into two groups; the control group was given routine treatment; the observation group was treated with trimetazidine and carvedilol on the basis of routine treatment; compared with the two groups after treatment Efficacy and left ventricular ejection fraction (LVEF), 6-minute walking distance (6MWT), heart failure score. Results: The total effective rate in the observation group was significantly higher than that in the control group (P <0.05). The levels of LVEF and 6MWT in the observation group were significantly higher than those in the control group and the heart failure scores were significantly lower than those in the control group (P <0.05) Obvious adverse reactions occurred. Conclusion: Trimetazidine combined with carvedilol in patients with rheumatic heart disease complicated with heart failure can significantly improve the efficacy and improve cardiac function.