随年龄的增长白细胞数目及淋巴细胞功能均有改变。但外周血中性粒细胞(PMN)的趋化移动(ChtM)是否随年龄而改变,尚未见报道。我们先前的工作表明,老年人白细胞糖皮质激素受体(GR)降低,但是否具生理学意义尚不明。为此,同时观察了白细胞GR及GR的效应指标—氢化考的松(F)对白细胞ChtM的抑制率(FI), With age, the number of white blood cells and lymphocyte function have changed. However, whether peripheral blood neutrophil (PMN) chemotactic migration (ChtM) changes with age has not been reported. Our previous work shows that the white blood cell glucocorticoid receptor (GR) is reduced in the elderly, but whether or not it has physiological significance is unknown. To this end, at the same time observed the effect of leukocyte GR and GR indicators - hydrocortisone (F) on the white blood cells ChtM inhibition rate (FI)