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虽然有关高温(hyperthermia)对于活细胞的作用研究已历时百余年,但对这种作用的机制远非完全了解。最近数年来,随着单独使用高温或与电离辐射联合应用治疗恶性肿瘤使得人们对高温研究又发生了兴趣。最近有证据表明,浆膜除了在决定细胞对辐射敏感性方面起着重要的作用之外,也是对高温损伤高度敏感的一种细胞结构。红细胞的细胞膜比较简单、没有细胞核、取材容易,所以是研究各种因素对膜作用的一个很好用的模型。本文主要用自旋标记技术
Although the study of the effects of hyperthermia on living cells has been going on for more than 100 years, the mechanism for this effect is far from being fully understood. In recent years, with the use of high temperatures alone or in combination with ionizing radiation for the treatment of malignant tumors, people have become interested in high temperature research. Recently, there is evidence that the serous membrane plays an important role in determining the radiosensitivity of cells, and is also a cell structure that is highly sensitive to hyperthermia. The cell membrane of red blood cells is relatively simple, has no nuclei, and is easy to draw. Therefore, it is a very good model for studying the effects of various factors on membranes. This article mainly uses spin labeling technology