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目的:探讨欣普贝生和米索前列醇在足月妊娠促宫颈成熟及引产中的有效性及安全性。方法:将124例孕晚期单胎头位有引产指征且宫颈Bishop评分<6分者随机分为米索组和欣普贝生组各62例,观察两组引产效果及对母儿的影响。结果:欣普贝生组临产时间、分娩时间均短于米索组,24 h内促宫颈成熟有效率及分娩率均高于米索组,但两组新生儿窒息率、剖宫产率无明显差异。结论:欣普贝生促宫颈成熟及引产效果优于米索前列醇。
OBJECTIVE: To investigate the efficacy and safety of Hinbubex and misoprostol in promoting cervical ripening and induction of labor during term pregnancy. Methods: One hundred and twenty-four cases with single fetus in the second trimester with indications of induction of labor and cervical Bishop scores <6 were randomly divided into two groups, 62 cases in each group. . Results: The time of labor and delivery were all shorter than those in misoprostol group. The effective rate of cervical ripening and delivery rate within 24 h were higher than that of misoprostol group. However, the rates of neonatal asphyxia, cesarean section rate Significant differences. Conclusions: Enxhibai is superior to misoprostol in promoting cervical ripening and induction of labor.