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目的为了解乙型脑炎灭活疫苗和减毒活疫苗的安全性、免疫学和流行病学效果。方法分析比较12年来不同地区使用不同疫苗监测所获得的数据。结果两种疫苗基础免疫和加强免疫后的免疫成功率差异无统计学意义、流行病学防制效果是相同的;但接种后副反应发生数乙脑灭活疫苗是减毒活疫苗的21.32倍。结论应优先将乙型脑炎减毒活疫苗纳入到儿童免疫规划中。
Objective To understand the safety, immunological and epidemiological effects of Japanese encephalitis inactivated and attenuated live vaccines. Methods Analyze and compare the data obtained from different vaccines surveillance in different regions over the past 12 years. Results There was no significant difference in the success rates of immunization and booster vaccination between the two vaccines, and the epidemiological control effect was the same. However, the incidence of side effects after vaccination was 21.32 times that of live attenuated vaccine . Conclusions Priority should be given to incorporating live attenuated JE vaccines into childhood immunization programs.