论文部分内容阅读
目的探索肾综合征出血热(HFRS)在南充市的流行规律与特征,为制定防制对策提供科学依据。方法统计历年HFRS疫情,开展动物密度、种群、带病毒率及人群抗体水平监测,并对其进行综合分析。结果45年来南充市HFRS平均发病率为4·30/10万,死亡率为0·18/10万,病死率为4·09%。发病率最高是三区(7·83/10万)、蓬安(6·52/10万)和营山(4·02/10万),发病呈现5-7月和10月至翌年1月2个高峰;年龄以16~55岁组为多(85·70%);职业以农民为高(78·50%),健康人群隐性感染率为3·31%;宿主动物以黑线姬鼠与褐家鼠为优势鼠种。鼠肺HFRS抗原阳性率为5·20%,鼠带病毒率以黄胸鼠、小家鼠、黑线姬鼠为高,黑线姬鼠与褐家鼠,褐家鼠与四川短尾带病率均有统计学意义。结论南充市是以姬鼠型为主的混合HFRS疫区,发病呈高度散发和相对集中的流行特点。主要宿主动物及传染源是黑线姬鼠与褐家鼠,HFRS发病与鼠类总密度和居住区内褐家鼠密度密切相关。
Objective To explore the prevalence and characteristics of hemorrhagic fever with renal syndrome (HFRS) in Nanchong City and to provide a scientific basis for making prevention and control measures. Methods The epidemic situation of HFRS over the years was analyzed. The monitoring of animal density, population, virus carrying rate and population antibody level were carried out. The comprehensive analysis was carried out. Results The average incidence of HFRS in Nanchong City was 45.30 / 100,000 in 45 years. The mortality rate was 0.18 / 100,000 and the case fatality rate was 4.09%. The highest incidence rates were in three districts (73.81 million), Peng’an (62.51 million) and Yingshan (4.102 / 100,000). The incidence rates ranged from May to July and from October to January of the following year (85.70%) in the age group of 16 to 55 years old, high (78.50%) in the occupation and 3.31% in the healthy population. The host animal, Rattus norvegicus is dominant mouse species. The positive rate of HFRS antigen in rat lung was 5.20%. The rate of virus in rat band was high in Rattus flavipectus, Mus musculus and Apodemus agrarius, while Apodemus agrarius and Rattus norvegicus, The rates were statistically significant. Conclusions Nanchong City is a mixed HFRS epidemic area mainly based on the Apodemus type. The incidence is highly epidemic and relatively concentrated. The main host animal and the source of infection are Apodemus agrarius and Rattus norvegicus. The incidence of HFRS is closely related to the total rat density and the brown rat density in the residential area.