目的探讨咽旁间隙肿瘤的诊断及最佳手术径路。方法 23例咽旁间隙肿瘤患者(良性肿瘤21例,恶性肿瘤2例)11例采用颈侧径路手术,12例采用颈腮腺径路手术。结果良性肿瘤21例中1例淋巴结核患者转院治疗,余均治愈;恶性肿瘤2例,术后随访2a以上患者均存活,肿瘤均未复发;术后均未发生严重并发症。结论 CT与MRI可为术前诊断和手术方案的制订提供重要参考依据,颈侧径路和颈腮腺径路是其主要手术径路。 Objective To investigate the diagnosis of parapharyngeal space tumors and the best surgical approach. Methods Twenty-three cases of parapharyngeal space tumors (21 cases with benign tumors and 2 cases with malignant tumors) were treated with lateral approach and 12 cases with cervical patellar glands. Results One case of benign tumors was transferred to hospital for treatment of lymphatic tuberculosis in 21 patients and was cured. In 2 patients with malignant tumors, all patients survived after 2 years of follow-up and all tumors did not recur. No serious complications occurred after surgery. Conclusion CT and MRI can provide important reference for the preoperative diagnosis and surgical plan. The cervical approach and the cervical parotid gland pathway are the main surgical approaches.