目的研究小半夏加茯苓汤的化学成分。方法利用硅胶、反相硅胶柱、薄层色谱和重结晶等方法对小半夏加茯苓汤进行分离、纯化,通过波谱数据对化合物进行结构解析。结果从小半夏加茯苓汤中分离纯化得到5个化合物,分别鉴定为6-Shogaol黄酮(1)、Kaempferol黄酮醇(2)、Leucine氨基酸(3)、β-sitosterol甾醇(4)、Guanosine嘌呤核苷(5)。结论化合物1~5均首次从小半夏加茯苓汤中得到。 Objective To study the chemical constituents of Xiaopanxia plus Poria Decoction. Methods Silica gel, reverse-phase silica gel column, TLC and recrystallization were used to separate and purify the Xiaobanxia plus Poria Decoction. The structure of the compound was analyzed by spectral data. Results Five compounds were isolated and purified from Pinellia Glabra decoction and identified as 6-Shogaol flavone (1), Kaempferol flavonol (2), Leucine amino acid (3), β-sitosterol sterol (4), Guanosine purine nucleus Glycoside (5). Conclusions Compounds 1 to 5 were obtained from Xiaoya Xia and Fu Ling Tang for the first time.