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目的观察雾化吸入布地奈德(普米克令舒)治疗小儿急性感染性喉炎的临床效果以及安全性。方法选取2015年3月-2016年10月医院收治的小儿急性感染性喉炎患者96例,随机分为观察组和对照组各48例。观察组患者在常规治疗基础上给予普米克令舒雾化吸入;对照组患者在常规治疗基础上给予氢化可的松琥珀酸钠静脉滴注。统计2组患者治疗效果、临床表现消失时间及不良反应发生情况。结果观察组患儿显效率和总有效率分别为45.83%和83.33%高于对照组的31.25%和62.50%,差异均有统计学意义(P<0.05)。观察组患儿发热、犬吠样咳嗽、吸气时哮鸣音、声嘶及吸气性呼吸困难等症状消失时间均明显短于对照组,差异均有统计学意义(P<0.05)。2组患者均无明显不良反应发生。结论雾化吸入普米克令舒治疗小儿急性感染性喉炎可取得较好效果,患儿的治疗有效率得以提高,治疗时间缩短,在缓解患儿病痛的同时也容易被患儿家属所理解和接受,具有重要的临床意义。
Objective To observe the clinical efficacy and safety of inhalation of budesonide (pulmicort respules) in the treatment of acute infection laryngitis in children. Methods A total of 96 children with acute respiratory laryngitis admitted to our hospital from March 2015 to October 2016 were randomly divided into observation group (48 cases) and control group (48 cases). Patients in the observation group were given inhalation of pulmicort respules on the basis of routine treatment. Patients in the control group were given intravenous hydrocortisone succinate on the basis of routine treatment. The treatment effect, the disappearance of clinical manifestations and the occurrence of adverse reactions in the two groups were statistically analyzed. Results The markedly effective rate and total effective rate in observation group were 45.83% and 83.33% respectively, which were significantly higher than those in control group (31.25% and 62.50%, P <0.05). The disappearance time of fever, bark-like cough, wheeze, hoarseness and inspiratory dyspnea in observation group were significantly shorter than those in control group (P <0.05). No adverse reactions occurred in both groups. Conclusion Pulmicorting Pulmicort Respiratory tract infection in children with acute treatment of laryngitis can achieve better results in children with improved treatment efficiency, shorter treatment time, ease the pain in children is also easily understood by the families of children and Accepted, has important clinical significance.