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目的探讨低氧条件下耐力运动对大鼠血浆三酰甘油的影响。方法选取雄性SD健康大鼠60只,随机分为6组,即常氧安静组(A)、常氧运动组(B)、低氧安静组(C)、高住高练组(D)、高住低练组(E)、低住高练组(F),A、B、F组在常氧下居住,C、D、E组在低氧下居住。模拟低氧舱内氧浓度为15.4%左右,相当于海拔2500m。B、E组每天以25m/min在常氧动物跑台上运动,D、F组每天以20m/min在相当于海拔2500m低氧环境动物跑台上运动。运动各组要求60min/d、6d/周,共实验6周。结果发现高住高练组、高住低练组和低住高练组与平原训练组相比较,三酰甘油浓度下降幅度更为明显,脂蛋白脂肪酶和骨骼肌脂蛋白脂肪酶的活性提高更明显。结论低氧训练对血脂代谢的改善与其提高了脂蛋白脂肪酶的活性紧密相关。
Objective To investigate the effect of endurance exercise on plasma triglyceride in rats under hypoxia. Methods Sixty male SD rats were randomly divided into six groups: normoxia group (A), normoxia group (B), hypoxia group (C) Living high and low training group (E), Living low training practice group (F), A, B, F group living under normoxia, C, D, E group living in hypoxia. The simulated oxygen concentration in the hypoxia chamber was about 15.4%, equivalent to an altitude of 2500m. Groups B and E were exercised daily at 25m / min on normoxic animals, while animals in groups D and F were mobilized at an altitude of 2500m an hour at 20m / min. Exercise groups require 60min / d, 6d / week, a total of 6 weeks of experiment. The results showed that the reduction of triglyceride concentration was more obvious and the activity of lipoprotein lipase and skeletal muscle lipoprotein lipase was higher in Living High Training Group, Living In Living Training Group and Living-in-Living Training Group Compared with Plain Training Group More obvious. Conclusion The improvement of lipids metabolism by hypoxia training is closely related to the increase of lipoprotein lipase activity.