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硝苯吡啶广泛应用于心绞痛的治疗,因其改善左心室功能,故又应用于陈旧性心肌梗塞的治疗。作者研究目的为测定陈旧性心肌梗塞患者口服硝苯吡啶休息与运动时的血液动力学变化。对象与方法 12例男性,平均年龄51岁(36-66),其中下壁梗塞6例,前壁和/或间壁5例,两者兼有1例。其中8例为单支、3例双支、1例三支血管病变。8例患者长期应用β-阻滞剂维持治疗。检查前,硝酸盐类、利尿剂、钙拮抗剂及抗心律失常药物停用48小时,地高辛停用72小时。检查时患者禁食,根
Nifedipine is widely used in the treatment of angina pectoris, because of its improvement of left ventricular function, it is also used in the treatment of old myocardial infarction. The aim of the study was to determine the hemodynamic changes of nifedipine during rest and exercise in patients with obsolete myocardial infarction. Subjects and Methods Twelve males, mean age 51 years (range, 36-66 years), including 6 cases of inferior wall infarction, 5 cases of anterior and / or interlobular wall, and 1 case of both. Of which 8 cases were single, three cases of double branch, one case of three vascular lesions. Long-term use of β-blocker maintenance therapy in 8 patients. Nitric acid, diuretics, calcium antagonists and anti-arrhythmic drugs were discontinued for 48 hours prior to exam and digoxin was discontinued for 72 hours. Patients were fasted during examination, root