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诱骗受体DcR3是较晚发现的肿瘤坏死因子超家族成员之一。DcR3能够抑制炎症反应和细胞凋亡,因此广泛参与了多种肿瘤和自身免疫性疾病的致病和发展过程。DcR3的这些特性也使其在疾病的诊断、治疗上具有较大的应用前景。笔者对DcR3的研究进展进行综述。
Latent receptor DcR3 is one of the later found members of the tumor necrosis factor superfamily. DcR3 is able to inhibit the inflammatory response and apoptosis, and is therefore widely involved in the pathogenesis and progression of a variety of oncological and autoimmune diseases. These characteristics of DcR3 also make it have a great application prospect in the diagnosis and treatment of diseases. The author reviews the research progress of DcR3.