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目的探讨局部晚期乳腺癌术前介入治疗与全身化疗的临床疗效差异性。方法选择局部晚期乳腺癌患者80例为研究对象,将所有患者随机分成观察组和对照组,每组40例,观察组术前采用介入治疗方法,对照组采用全身化疗方法,比较两组患者治疗效果及不良反应情况。结果两组患者经治疗后患者乳腺肿块大小明显缩小,肿瘤症状明显改善,且观察组(介入治疗)改善效果明显优于对照组,表明治疗前后组内和组间差异均具有统计学意义(P<0.05);两组患者均发生不同程度的不良反应,且对照组不良反应发生率明显多于观察组,组间差异具有统计学意义(P<0.05)。结论局部晚期乳腺癌患者采用介入方法治疗,可以有效缩小肿块大小,具有疗效显著、副作用小等优点,对提高患者生活质量和延长生存周期具有十分重要的意义。
Objective To investigate the difference of clinical efficacy between preoperative interventional therapy and systemic chemotherapy in locally advanced breast cancer. Methods Eighty patients with locally advanced breast cancer were selected as study subjects. All patients were randomly divided into observation group and control group, 40 cases in each group. The observation group was treated with interventional therapy before operation, while the control group was treated with systemic chemotherapy. Effects and adverse reactions. Results The size of breast tumor was significantly reduced and tumor symptoms were significantly improved in both groups after treatment. The improvement effect of the observation group (interventional treatment) was obviously better than that of the control group, indicating that the difference between the two groups was statistically significant (P <0.05). Adverse reactions were observed in both groups and the incidence of adverse reactions in the control group was significantly higher than that in the observation group. The difference between the two groups was statistically significant (P <0.05). Conclusion The treatment of locally advanced breast cancer patients with interventional methods can effectively reduce the size of the tumor, with the advantages of significant curative effect and small side effects, which are of great significance to improve patients’ quality of life and extend the life cycle.