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用蔗糖作辅助铁水，饲养刚离乳的Sprague－Dawley雄性大鼠，180天后，53％大鼠肥胖成为饮食诱发肥胖型大鼠（DIO大鼠），47％大鼠不肥胖成为饮食诱发肥胖抵抗型大鼠（DIO－R大鼠）且DIO和DIO－R大鼠均具高脂血症。说明25％蔗糖可诱发Sprague-Dawley雄性大鼠肥胖病高脂血症，但同样条件下为什么部分大鼠不肥胖还有待于进一步研究。另外，对DIO大鼠的肥胖机制作了初步探讨。
Fifty-three percent of rats were obese as diet-induced obese rats (DIO rats) 180 days after supplementation with sucrose as an adjunct to hot metal in Sprague-Dawley male rats, and 47% of the rats became obese as diet-induced obesity Type rat (DIO-R rat) and both DIO and DIO-R rats have hyperlipidemia. It shows that 25% sucrose can induce obesity and hyperlipidemia in male Sprague-Dawley rats, but why some rats are not obese under the same conditions remains to be further studied. In addition, the mechanism of obesity in DIO rats was explored.