China’s aerospace industry is facing a major task of increasing the reform of aerospace management system and speeding up civil-military integration, which leads to an urgent demand for new aerospace think tank products. Thankfully, with “information space” as the carrier, the “systems science” as the guidance, and QIAN Xuesen’s “metasynthetic wisdom system” as the core, QIAN Xuesen think tank provides the decision support for China to develop an aerospace knowledge economy and to continuously enhance the “space soft power”. In this paper, the framework of the meta-synthetic wisdom system guided by systems science is presented, the relationship between basic ideas of QIAN Xuesen think tank and meta-synthetic wisdom system is explained and the construction items of aerospace hall of the workshop for meta-synthetic engineering(aerospace HWMSE) are analyzed. China’s aerospace industry is facing a major task of increasing the reform of aerospace management system and speeding up civil-military integration, which leads to an urgent demand for new aerospace think tank products. Thankfully, with “information space ” as the carrier, the “systems science ” as the guidance, and QIAN Xuesen’s “metasynthetic wisdom system ” as the core, QIAN Xuesen think tank provides the decision support for China to develop an aerospace knowledge economy and to continuously enhance the “space soft power ”. In this paper, the framework of the meta-synthetic wisdom system guided by systems science is presented, the relationship between basic ideas of QIAN Xuesen think tank and meta-synthetic wisdom system is explained and the construction items of aerospace hall of the workshop for meta-synthetic engineering (aerospace HWMSE) are analyzed.