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目的探讨阿奇霉素联合甲硝唑治疗急性盆腔炎的临床效果。方法回顾性分析汕头市澄海区人民医院于2015年3月-2017年3月收治的82例急性盆腔炎患者的临床资料,将入组的患者根据随机抽签原则分为对照组和研究组,每组41例,对照组采用头孢拉啶联合甲硝唑治疗,研究组采用阿奇霉素联合甲硝唑治疗,比较两组患者的临床疗效及不良反应发生情况。结果研究组治疗总有效率为92.68%高于对照组的73.17%,差异有统计学意义(P<0.05);研究组与对照组治疗前的盆腔包块面积比较,差异无统计学意义(P>0.05);治疗后两组盆腔包块面积均缩小,但与对照组比较,研究组缩小的更为显著,差异有统计学意义(P<0.05);研究组不良反应发生率为7.32%明显低于对照组的21.95%,差异有统计学意义(P<0.05)。结论阿奇霉素联合甲硝唑治疗急性盆腔炎疗效显著,且不良反应少,值得临床推广应用。
Objective To investigate the clinical effect of azithromycin combined with metronidazole in the treatment of acute pelvic inflammatory disease. Methods The clinical data of 82 patients with acute pelvic inflammatory disease admitted to Chenghai People’s Hospital of Shantou City from March 2015 to March 2017 were retrospectively analyzed. According to the principle of random lottery, the patients were divided into control group and study group. Group, 41 cases. The control group was cephradine combined with metronidazole. The study group was treated with azithromycin combined with metronidazole. The clinical efficacy and adverse reactions of the two groups were compared. Results The total effective rate of study group was 92.68%, which was significantly higher than that of control group (73.17%, P <0.05). There was no significant difference in pelvic mass area between study group and control group before treatment (P > 0.05). After treatment, the area of pelvic mass in both groups shrank, but the reduction in the study group was more significant than that in the control group (P <0.05). The incidence of adverse reactions in the study group was 7.32% Lower than 21.95% of the control group, the difference was statistically significant (P <0.05). Conclusion Azithromycin combined with metronidazole in the treatment of acute pelvic inflammatory disease significant effect, and fewer adverse reactions, worthy of clinical application.