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目的探讨甘精胰岛素应用于独居的老年2型糖尿病患者的依从性和疗效。方法 32例独居的老年2型糖尿病患者在原来口服药不变的基础上,加用每天1次甘精胰岛素治疗3个月。结果观察组和对照组的空腹血糖(FBG)分别下降(2.6±1.5)mmoL/L 和(0.3±0.1)mmoL/L(t=1.691,P<0.05);糖基化血红蛋白(HbA_1c)分别下降(1.4±0.6)%和(0.4±0.1)%(t=2.231,P<0.05);低血糖发生人次分别为6次和4次,均非严重低血糖。结论甘精胰岛素可以提高独居的老年2型糖尿病患者的依从性和疗效。
Objective To investigate the compliance and efficacy of insulin glargine in elderly type 2 diabetic patients living alone. Methods Thirty-two elderly patients with type 2 diabetes living alone were treated with insulin glargine once a day for 3 months on the basis of the same oral medication. Results The fasting blood glucose (FBG) in the observation group and the control group decreased (2.6 ± 1.5) mmoL / L and (0.3 ± 0.1) mmoL / L respectively (t = 1.691, P < (1.4 ± 0.6)% and (0.4 ± 0.1)% respectively (t = 2.231, P <0.05). The incidences of hypoglycemia were 6 times and 4 times respectively, which were not serious hypoglycemia. Conclusion Glargine can improve the compliance and efficacy of elderly type 2 diabetic patients living alone.