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目的:分析普外科围术期患者抗菌药物的使用情况。方法:选取医院2012年7月—2014年7月间普外科围术期患者的病例资料500例,回顾性分析患者围术期使用抗菌药物类型、使用时间以及是否存在不合理用药情况等。结果:根据围术期抗菌药物使用率,依序排名为头孢菌素类、青霉素类、氨基糖苷类、氟喹诺酮类、大环内酯类及硝基咪唑类,其中预防性用药为418例,治疗性用药为82例;术后停药时间为3~7 d为145例,停药时间超过7 d为355例;用药合理者为170例,基本合理者为300例,不合理者为30例;不合理的主要原因为用药时间过长、用药时机不当及药物类型选择不当。结论:普外科患者围术期抗菌药物的使用属基本合理,但仍应严格其管理,以确保患者用药合理和安全。
Objective: To analyze the use of antimicrobials in perioperative period in general surgery. Methods: A total of 500 cases of perioperative patients during the perioperative period were selected from July 2012 to July 2014 in our hospital. The types of antimicrobial agents used perioperatively, the time of their use and the irrational use of drugs were retrospectively analyzed. Results: According to the perioperative antibacterial drug use rates, cephalosporins, penicillins, aminoglycosides, fluoroquinolones, macrolides and nitroimidazoles were ranked in order, of which 418 were prophylactic, Therapeutic drug use was 82 cases; the duration of postoperative withdrawal was from 3 to 7 days, and the withdrawal time was over 7 days, 355 cases. The reasonable medication was 170 cases, with 300 cases being reasonable and 30 cases unreasonable Example; the main reason for irrational medication for too long, improper timing of medication and improper selection of drug types. Conclusion: The use of antimicrobial agents in general surgery patients is basically reasonable, but should be strictly managed to ensure rational and safe medication for patients.