很多化学和物理因素可以损伤人体细胞中的染色体,使其产生断裂、粘连、内复制增多等。我们对再生障碍性贫血患者作细胞遗传学研究的目的在于了解本病的发病原理,确定某些药物或化学、物理因素引起再生障碍性贫血的性质,从而可以更有效地预防和治疗本病。此外,对继发性再生障碍性贫血可能提供一种客观的检查指标。现将我们一年多来的初步研究结果报道如下。 Many chemical and physical factors can damage the chromosomes in human cells, causing them to break, attach, and multiply inside. The purpose of our cytogenetics study on patients with aplastic anemia is to understand the pathogenesis of this disease and to determine the nature of aplastic anemia caused by certain drugs or chemical and physical factors so that the disease can be prevented and treated more effectively. In addition, secondary aplastic anemia may provide an objective test indicators. Now we have more than a year of preliminary findings reported below.