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作者研究了由流感病毒 H5N1 A/香港 /1 56 / 97( HK/ 1 56 )衍生的重组 H5血凝素( HA)疫苗对人体的安全性及免疫原性。 杆状病毒表达的重组 H5HA由无血清培养 Spotoptera frugiperda昆虫细胞获得。重组 H5疫苗 ( r H5)经物理及层析方法纯化 ,纯度大于 95%。用含 0 .0 1 % Tw
The authors studied the safety and immunogenicity of a recombinant H5 hemagglutinin (HA) vaccine derived from the influenza virus H5N1 A / Hong Kong / 1 56/97 (HK / 1 56) on humans. Baculovirus expressed recombinant H5HA was obtained from serum-free Spotoptera frugiperda insect cells. Recombinant H5 vaccine (r H5) was purified by physical and chromatographic methods with a purity greater than 95%. Contains 0 .0 1% Tw