中毒性休克综合征是一种严重的疾病,它多发生于行经期妇女,其原因尚不十分明确,一般认为与应用阴道栓塞物和金黄色葡萄球菌感染有关。其临床表现为突发高热(38.9℃);伴有呕吐、腹泻(水样)、肌痛,继而出现低血压(90mmHg),重者休克;急性期出现弥散性晒伤样红斑;病后(1～2周)出现脱皮,特别是手掌和足底部明显。有3个或更多的器官系统受损害,如肌肉、粘膜(阴道、口咽、眼结膜)、肾脏、肝、血液、中枢神经;但血液、咽部培养和血浆效价滴定试验皆为阴性。1980年Schrock首次报告3例妇女患者(1例死亡)均发生在月经期或经期刚过。据统计在行经期妇女,本病发病率每年约为10～15/100,000,且患者皆为经期采用阴道栓塞法 Toxic shock syndrome is a serious disease, which occurs mostly in women during menstruation, the reason is not yet very clear, generally considered associated with the application of vaginal embolization and Staphylococcus aureus infection. The clinical manifestations of sudden high fever (38.9 ℃); associated with vomiting, diarrhea (watery), myalgia, followed by hypotension (90mmHg), severe shock; acute diffuse sunburn erythema; 1 to 2 weeks) appear peeling, especially the palms and feet at the bottom of the obvious. There are 3 or more of the organ system damage, such as muscle, mucous membrane (vagina, oropharynx, conjunctiva), kidney, liver, blood, central nervous system; but blood, pharyngeal culture and plasma titer test were negative . Schrock first reported in 1980 that three women (1 death) had their menstrual period or menstrual period just past. According to statistics in women during menstruation, the incidence of this disease is about 10 ~ 15 / 100,000 per year, and patients are menstrual vaginal embolization