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目的探讨放疗前后脑内肿瘤的ＭＲＩ变化，以客观评价放疗的疗效。方法对５１例脑内肿瘤（１０例松果体区肿瘤，１９例脑转移瘤和２２例胶质瘤）放疗前后进行ＭＲ平扫和增强扫描，比较放疗前后肿瘤大小、占位效应、瘤周水肿及肿瘤内部改变。结果５１例肿瘤放疗后症状改善４２例（占８２．５％），９例（１７．６％）症状加重，而ＭＲＩ示肿瘤缩小有３７例（７２．５％），其中６例完全消失，９例肿瘤大小不变，５例增大；占位效应缩小或消失３９例（占７６．５％）；瘤周水肿缩小或消失有４０例（７８．４％）。４例临床症状加重而ＭＲＩ表现为放射性脑病。结论ＭＲＩ为一种能客观反映放疗前后脑肿瘤变化的无创性的敏感方法。
Objective To investigate the MRI changes of brain tumors before and after radiotherapy to evaluate the curative effect of radiotherapy objectively. Methods 51 cases of intracranial tumors (10 pineal tumors, 19 brain metastases and 22 gliomas) were scanned by MRI before and after radiotherapy. The tumor size, mass effect, tumor size Edema and tumor internal changes. Results Twenty-one patients (82.5%) had symptoms improvement after radiotherapy in 51 patients, and 9 patients (17.6%) had symptoms aggravated. MRI showed 37 patients (72.5%) with tumor shrinkage, of which 6 patients disappeared completely, 9 cases of tumor size unchanged, 5 cases increased; space effect reduced or disappeared in 39 cases (76.5%); peritumoral edema shrink or disappear in 40 cases (78.4%). 4 cases of clinical symptoms and MRI manifestations of radiation encephalopathy. Conclusion MRI is a noninvasive and sensitive method that can objectively reflect the changes of brain tumors before and after radiotherapy.