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目的 评价131IGSPECT/CT断层显像对分化型甲状腺癌(DTC)术后良恶性摄碘灶的鉴别作用.方法 118例DTC术后患者行131I清除残留甲状腺(残甲)治疗,之后5~7d同时行131IG全身平面显像(WBS)和131IGSPECT/CT断层显像.比较131IGWBS和131IGSPECT/CT对DTC转移灶的检出能力以及对摄碘灶定位、定性能力的差别.结果131IGWBS发现255处异常摄碘灶,诊断转移灶的灵敏度、特异性和准确性分别为8406%、8671%和8508%;131IGSPECT/CT发现333处异常摄碘灶,诊断转移灶的灵敏度、特异性和准确性分别为9881%、9942%和9902%;两者之间的差异有统计学意义(P均<005).131IGWBS发现的449处摄碘灶中正确率为7884%;131IGSPECT/CT发现的509处摄碘灶中正确率为9902%.结论 131IGSPECT/CT相较131IGWBS对DTC转移灶的诊断灵敏度、特异性和准确性更高,对于残甲和DTC转移、复发灶以及良性碘摄取的鉴别诊断准确性更高,可以为131I治疗DTC提供更为准确的定位和定性的信息.
Objective To evaluate the differential diagnosis of benign and malignant iodine-iodine lesions in differentiated thyroid cancer (DTC) after 131 IECT / CT imaging.Methods Totally 118 patients with DTC were treated with 131I to remove residual thyroid (residual thyroid) Line 131IG whole-body imaging (WBS) and 131IGSPECT / CT imaging were performed.Results The detection of 131I DTC and 131IGSPECT / CT on DTC metastasis and the difference of their localization and qualitative ability were compared.Results There were 255 abnormal images The sensitivity, specificity and accuracy of iodine and diagnostic metastasis were 8406%, 8671% and 8508% respectively. The sensitivity, specificity and accuracy of 333 iodine lesions detected by 131IG SPECT / CT were 9881 %, 9942% and 9902%, respectively. The difference between the two groups was statistically significant (P <0.005). The correct rate was found in 449 iodine-contaminated sites in 131 IWBS and 7884% , The correct rate was 9902% .Conclusion The diagnostic sensitivity, specificity and accuracy of 131IGSPECT / CT compared with 131IGWBS in DTC metastasis are higher, and the diagnostic accuracy is better for the diagnosis of residual and DTC metastasis, recurrence and benign iodine , Which can provide more accurate DTC for 131I treatment Positioning and qualitative information.