疾病的地区分布模式和家庭集聚性研究是流行病学推论过程中确立统计关联的重要方法之一,对病因探索具有定向指导意义。作者试用负二项分布模型在拟合麻风病地区和家庭集聚性分布模式上获得成功,此外还简要介绍了二项分布模型、泊松分布模型、标化方差分析、G 检验法的实际应用。 Regional distribution of disease and family agglomeration research is one of the important methods to establish statistical correlation in the process of epidemiological deduction, and it is of guiding significance for the etiological exploration. The authors try the negative binomial distribution model to be successful in fitting leprosy area and family agglomeration distribution patterns. In addition, the binomial distribution model, Poisson distribution model, standardized variance analysis and G-test are also briefly introduced.