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本实验表明:松萝酸钠对呼吸道常见致病菌有较强的抑制作用,临床上它对慢性气管炎的疗效可能主要与其抑菌作用有关。本实验用大鼠、犬的急性毒性试验或大白鼠的亚急性毒性实验均未能证实文献称述的松萝酸钠的作用相似于二硝基酚,即引起体温上升,血糖升高,造血功能障碍等。小鼠LD_(50)的剂量,口服量为静脉注射量的5.6倍,小鼠用口服LD_(50)量的1/4～1/6,连用18天,大鼠用口服致死量的1/2～1/6,连用30天,
This experiment shows that sodium usnicosa has a strong inhibitory effect on common pathogens of the respiratory tract, and its clinical efficacy on chronic bronchitis may be mainly related to its antibacterial effect. The experimental rat or dog acute toxicity test or the subacute toxicity test of rats failed to confirm that the role of sodium rosinate described in the literature is similar to that of dinitrophenol, that is, the increase in body temperature, blood glucose, and hematopoietic function. Obstacles and so on. Dosage of mouse LD_(50) was 5.6 times that of intravenous injection, and 1/4 to 1/6 of oral LD_(50) was administered to mice for 18 consecutive days. Rats were given an oral lethal dose of 1/ 2 to 1/6, for 30 days