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目的:探讨中药汤剂治疗术后转移性乳腺癌的临床疗效。为中药临床治疗转移性乳腺癌提供数据支持。方法:选取2008年6月至2012年6月我院收治的80例转移性乳腺癌患者,随机分成两组,其中,对照组40例,采用典型根治术或改良根治术治疗,术后根据不同患者特点给予相应配伍的中药汤剂配合治疗;观察组40例,采用与对照组相同的手术进行治疗,术后服用来曲唑2.5mg/天配合治疗。结果:术后治疗一周治疗组发生恶心反应4例,发热反应7例,对照组分别为5例、11例。两组相比具有统计学差异(χ2=7.545,P<0.01)。比较术后两组无病间期,治疗组患者乳癌根治术后无病间期<2年的7例,2-5年的33例,对照组患者无病间期<2年的17例,2-5年的23例,两组相比具有统计学差异(χ2=5.878,P<0.05)结论:采用中药汤剂治疗转移性乳腺癌疗效显著,值得大力推广。
Objective: To investigate the clinical curative effect of traditional Chinese medicine decoction on postoperative metastatic breast cancer. To provide clinical data for traditional Chinese medicine treatment of metastatic breast cancer. Methods: Eighty patients with metastatic breast cancer who were admitted to our hospital from June 2008 to June 2012 were randomly divided into two groups. Among them, 40 patients in the control group were treated with typical or modified radical mastectomy, Patients with appropriate compatibility of the Chinese medicine decoction with the treatment group; observation group of 40 patients with the same surgery as the control group, after taking letrozole 2.5mg / day with the treatment. Results: One week after the operation, nausea reaction occurred in 4 cases, fever in 7 cases, control group were 5 cases and 11 cases. There was a statistically significant difference between the two groups (χ2 = 7.545, P <0.01). Seven patients with disease-free period <2 years, 33 patients with 2-5 years after radical mastectomy, 17 patients with disease-free period <2 years in control group, 23 cases of 2-5 years, the two groups was statistically significant (χ2 = 5.878, P <0.05) Conclusion: The treatment of metastatic breast cancer with Chinese medicine decoction significant effect, it is worth promoting.