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目的:探讨临床药师在2型糖尿病治疗中的作用,为临床药师对糖尿病患者开展临床药学服务提供依据和参考。方法:将48例患者分为两组:对照组(24例)与研究组(24例)。对照组患者进行常规治疗,研究组患者除接受医师、护士的治疗外,另接受临床药师制定的个体化干预措施,包括出院后每月1次的电话随访干预等。于出院后3个月及6个月,检验并记录两组患者的各项临床检验指标,包括FPG、糖化血红蛋白(HbA1c),根据治疗前后各项指标变化、不良反应发生率等评价临床药师干预在2型糖尿病治疗中的作用。结果:研究组患者出院后3个月及6个月患者的FPG、HbA1c水平均显著低于对照组,两组比较差异有统计学意义(P<0.05);对照组不良反应发生率为8.33%(2/24),研究组未发生不良反应,两组比较差异有统计学意义(P<0.05)。结论:临床药师参与2型糖尿病患者的治疗,制订个体化的给药方案并指导用药能明显提高血糖达标率,值得推广应用。
Objective: To explore the role of clinical pharmacists in the treatment of type 2 diabetes and provide the basis and reference for clinical pharmacists to carry out clinical pharmacy services for patients with diabetes. Methods: 48 patients were divided into two groups: control group (24 cases) and study group (24 cases). Patients in the control group were treated routinely. Patients in the study group received individualized interventions prescribed by clinical pharmacists, including telephone follow-up once a month after hospital discharge, in addition to receiving physicians and nurses. At 3 months and 6 months after discharge, all the clinical tests, including FPG and HbA1c, were tested and recorded. The clinical pharmacist interventions were evaluated according to the changes of various indexes before and after treatment and the incidence of adverse reactions Role in the treatment of type 2 diabetes. Results: The levels of FPG and HbA1c in study group were significantly lower than those in control group at 3 months and 6 months after discharge. There was significant difference between the two groups (P <0.05). The incidence of adverse reactions in control group was 8.33% (2/24). There was no adverse reaction in the study group, the difference was statistically significant (P <0.05). Conclusion: The participation of clinical pharmacists in the treatment of type 2 diabetes patients, the development of individualized dosing regimens and the guidance of medication can significantly improve the compliance rate of blood glucose, which is worth popularizing and applying.