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利用果蝇的复眼为观察对象来阐明一种新的Mob超家族蛋白——Mats(mob as tumor suppressor) 的肿瘤抑制功能。Mob家族是一个庞大的蛋白家族,自第1个Mob基因——mobl在酵母中被克隆以来,在原生物到动物的各种生物中已发现并确定了超过130种的Mob家族成员,然而大多数的mob基因的功能尚不明确。本研究首次在果蝇3号染色体的94A12区
The compound eye of Drosophila was used as the observation object to elucidate the tumor suppressor function of a new Mob superfamily protein called mob as tumor suppressor. The Mob family, a large family of proteins, has identified and identified more than 130 members of the Mob family in various organisms from the primitive to the animal since the first Mob gene, mobl, was cloned in yeast, whereas most The function of the mob gene is not yet known. This study is the first in the 94A12 region of Drosophila chromosome 3