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目的探讨奥扎格雷纳治疗急性缺血性卒中的疗效及不良反应。方法急性缺血性卒中患者244例,随机分为观察组144例和对照组100例。观察组用奥扎格雷纳80 mg,加入5%葡萄糖溶液或生理盐水250 ml,静脉滴注,2次/d;对照组100例,用脉络宁20 ml,加入5%葡萄糖溶液或生理盐水250 ml,静脉滴注,1次/d,两组疗程均为14 d。比较两组临床疗效及不良反应。结果观察组总有效率85.7%,明显高于对照组67.8%,差异有统计学意义(P<0.01),两组治疗期间均未出现明显反应。结论奥扎格雷纳治疗急性缺血性卒中疗效好,值得推广和应用。
Objective To investigate the efficacy and adverse reactions of Ozagrenal in the treatment of acute ischemic stroke. Methods 244 patients with acute ischemic stroke were randomly divided into observation group 144 cases and control group 100 cases. Observation group with Ozagrenault 80 mg, added 5% glucose solution or normal saline 250 ml, intravenous infusion, 2 times / d; control group of 100 patients with Mailuoning 20 ml, adding 5% glucose solution or saline 250 ml, intravenous infusion, 1 time / d, the two groups of treatment were 14 d. The clinical efficacy and adverse reactions of the two groups were compared. Results The total effective rate in the observation group was 85.7%, which was significantly higher than that in the control group (67.8%) (P <0.01). No significant reaction was observed during the two groups. Conclusion Ozagrel is effective in treating acute ischemic stroke and is worth popularizing and applying.