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目的:比较真性血管瘤的平阳霉素局部注射联合普萘洛尔口服、单独平阳霉素局部注射、单独普萘洛尔口服3种保守治疗方法的临床效果。方法:将62例真性血管瘤患者分为A组22例:采用平阳霉素局部注射联合普萘洛尔口服治疗,B组20例采用单独平阳霉素局部注射治疗,C组20例采用单独普萘洛尔口服治疗。结果:治疗后1～2年随访观察,按Achauer 4级评分法评价疗效。A组治疗优良率为90.9%;B组治疗优良率为80.0%;C组治疗优良率为70.0%。3种治疗组间存在显著性差异(P<0.05)。结论:真性血管瘤的3种保守治疗方法中,平阳霉素局部注射联合普萘洛尔口服是治疗真性血管瘤最有效的治疗方法,值得临床推广应用。
OBJECTIVE: To compare the clinical efficacy of oral pingyangmycin injection, propranolol alone injection and propranolol oral administration alone in the treatment of true hemangioma with oral administration of propranolol. Methods: Twenty-two patients with true hemangioma were divided into group A (n = 22): local administration of pingyangmycin combined with propranolol orally, group B (n = 20) were treated with local injection of pingyangmycin, and group C Azadirachtin oral treatment. Results: After 1 to 2 years of follow-up, the Achauer 4-grade score was used to evaluate the efficacy. The excellent and good rate was 90.9% in group A, 80.0% in group B and 70.0% in group C. There was a significant difference between the three treatment groups (P <0.05). CONCLUSION: Among the three conservative treatments of true hemangiomas, Pingyangmycin injection combined with propranolol orally is the most effective treatment for true hemangiomas, which is worthy of clinical application.