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目的观察中药经皮给药治疗小儿轮状病毒肠炎的临床疗效。方法选择2010年1月至2011年12月住院患儿,年龄6个月至2岁的急性轮状病毒肠炎140例,并随机分为对照组60例,以纠正脱水、酸中毒,口服补液盐(ORS)和抗病毒口服思密达治疗;治疗组80例在对照治疗基础上,加用中药经皮给药治疗。结果显效率、总有效果率治疗组分别为61.3%和91.3%,对照组分别为18.3%和66.7%,经统计学检验差异有统计学意义(P<0.01)。结论中药经皮给药治疗小儿轮状病毒肠炎有良好效果。
Objective To observe the clinical efficacy of transdermal drug delivery in children with rotavirus enteritis. Methods From January 2010 to December 2011, 140 hospitalized children with acute rotavirus enteritis aged 6 months to 2 years were randomly divided into control group (60 cases) to correct dehydration, acidosis, oral rehydration salt (ORS) and anti-virus oral Smectite treatment group; 80 cases in the treatment group based on the control treatment, plus traditional Chinese medicine percutaneous administration. Results The effective rate and the total effective rate were 61.3% and 91.3% in the treatment group and 18.3% and 66.7% in the control group, respectively. The difference was statistically significant (P <0.01). Conclusion Chinese transdermal drug treatment of children with rotavirus enteritis has a good effect.