四环素为临床常用的抗菌素,对其抗菌作用及原理和临床应用方面已有充分的研究。四环素对免疫功能的影响,报导资料较少。我们用小鼠腹腔巨噬细胞法,探讨了四环素对巨噬细胞吞噬功能的影响。现报告如下: 实验方法及结果一、实验药物 1.四环素:盐酸四环素针剂,广西桂林第二制药厂生产,批号7703113,用蒸馏水配成0.2％溶液,按30mg/kg/天灌胃给药。 2.左旋咪唑:盐酸盐片剂,广东石岐制药 Tetracycline is a commonly used clinical antibiotics, its antibacterial effect and principles and clinical applications have been fully studied. Tetracycline on the immune function, reported less information. We use mouse peritoneal macrophage method to explore the tetracycline macrophage phagocytosis. The report is as follows: Experimental methods and results I. Experimental drugs 1. Tetracycline: tetracycline hydrochloride injection, Guilin, Guangxi Second Pharmaceutical Factory production, batch number 7703113, with distilled water dubbed 0.2% solution, administered by gavage 30mg / kg / day. 2. Levamisole: hydrochloride tablets, Guangdong Shiqi Pharmaceutical