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目的了解外科围术期抗菌药物预防应用情况变化趋势,为制定抗菌药物管理策略提供科学数据。方法采用横断面调查的方法,对某医院2010、2011和2012年某一天住院手术患者围术期抗菌药物的预防应用情况进行调查。结果 2010、2011和2012年调查当日手术患者围手术期抗菌药物使用率依次为98.8%、90.4%和88.1%;其中Ⅰ类手术切口围手术期预防用药率分别为99%、85.7%和75.7%,均呈现下降趋势。Ⅰ类手术切口术前0.5~2 h给药率则呈上升趋势,分别为78.4%、86.1%和89.1%。3次调查用药频率第一位的抗菌药物分别是第三代头孢、头霉素类和第一代头孢。结论该医院住院手术患者围术期抗菌药物预防用药率逐年下降,使用趋向合理。
Objective To understand the trend of the prevention and the application of antimicrobial agents during surgical perioperative period and provide scientific data for the development of antimicrobial drug management strategies. Methods A cross-sectional survey was conducted to investigate the prevention and treatment of perioperative antibiotics in hospitalized patients on one day in 2010, 2011 and 2012 in a hospital. Results The perioperative antibacterials utilization rate of surgical patients in the survey was 98.8%, 90.4% and 88.1% respectively on the day of investigation in 2010, 2011 and 2012. The perioperative prophylaxis rates for class I surgical incision were 99%, 85.7% and 75.7% , All showed a downward trend. Class Ⅰ surgical incision preoperative 0.5 ~ 2 h dosing rates showed an upward trend, were 78.4%, 86.1% and 89.1%. Three times the frequency of the first antimicrobial drug investigation were third-generation cephalosporins, cephamycins and first-generation cephalosporins. Conclusion The perioperative antibiotic prophylaxis rate of hospitalized patients in this hospital declines year by year, and the use trend is reasonable.