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目的为了解沙眼衣原体、人型支原体、解脲支原体感染所致非淋球菌性尿道炎 (NGU)的流行状况和分布特征。方法对246例 (男142例 ,女102例 )NGU患者 ,用斑点酶免疫渗滤法检测泌尿生殖道标本的沙眼衣原体抗原 ;用肉汤培养法检测人型支原体、解脲支原体 ,同时做解脲支原体的药敏。结果衣原体阳性47例 (19.1 % ) ,人型支原体阳性13例 ,解脲支原体阳性81例 ,同一标本检出两种支原体11例。支原体感染率在不同性别中有显著差异 (p<0.01) ;衣原体感染率在不同性别中无明显差异。解脲支原体的药敏提示对强力霉素、四环素、原始霉素、交沙霉素高度敏感 ,敏感率均>90 %。结论临床考虑NGU应同时检测解脲支原体和沙眼衣原体。强力霉素和四环霉素可作疑似GNU的经验用药。
Objective To understand the prevalence and distribution of non-gonococcal urethritis (NGU) caused by Chlamydia trachomatis, Mycoplasma hominis and Ureaplasma urealyticum infection. Methods 246 cases (male 142 cases, female 102 cases) of NGU patients were tested for genital C. trachomatis antigens in genitourinary tract by dot enzyme immunoprecipitation. Mycoplasma hominis and Ureaplasma urealyticum were detected by broth culture method. Ureaplasma urealyticum drug sensitivity. Results Chlamydia positive in 47 cases (19.1%), Mycoplasma hominis in 13 cases, 81 cases of positive Ureaplasma urealyticum, the same specimen detected two kinds of mycoplasma in 11 cases. Mycoplasma infection rate in different sex have significant differences (p <0.01); chlamydia infection rate in different gender no significant difference. Ureaplasma urealyticum drug sensitivity tips for doxycycline, tetracycline, pristinamycin, josamycin high sensitivity, sensitivity rates were> 90%. Conclusions Clinical Considerations NGU should simultaneously detect Ureaplasma urealyticum and Chlamydia trachomatis. Doxycycline and tetracycline can be used as suspected GNU empirical medication.