本文报道了在第二次世界大战期间,曼哈顿计划中钚工作者26例42年的随访结果.1987年做了全面的医学检查及剂量估算,未见死亡数增加.3例死于肺癌(均有吸烟史),仍在预期值之中.1例死于骨肉瘤,是钚受照人员的首例报告.发生在骶骨、非骨肉瘤的好发部位,潜伏期43年,其体内钚沉积量为560Bq(15nCi),骨表面剂量比辐射防护标准要低. This article reports on the 42-year follow-up of plutonium workers in the Manhattan program during World War II.26 A complete medical examination and dose estimation were performed in 1987, with no increase in deaths, 3 deaths from lung cancer (both There is a smoking history), still in the expected value.One died of osteosarcoma, is the first report of plutonium irradiated personnel occurred in the sacrum, non-osteosarcoma prone site, the incubation period of 43 years, the body of plutonium deposition For 560Bq (15nCi), the bone surface dose is lower than the radiation protection standard.