再灌注有利于缺血或缺氧器官的生存,但再灌注的建立也会导致组织进一步的损伤。实验发现将猫的肠系膜上动脉结扎3小时,再恢复灌流1小时后粘膜损伤的程度比持续4小时的缺血更严重。缺血3小时后去氧血流的再灌注就不会导致进一步的损伤,这些提示氧及其反应性的代谢产物参与再灌注 Reperfusion is conducive to the survival of ischemic or hypoxic organs, but the establishment of reperfusion will lead to further tissue damage. The experiment found that the cat’s superior mesenteric artery ligation 3 hours, and then resume perfusion 1 hour after mucosal injury more than 4 hours of ischemia is more serious. Reperfusion of deoxygenated blood flow 3 h after ischemia did not result in further damage, suggesting that oxygen and its reactive metabolites are involved in reperfusion